Saturday’s Premier League action concludes at the Amex Stadium where newcomers Brighton and Hove Albion face title favourites Manchester City.

The Seagulls last match in the top flight came at home against the Citizens, with the visitors running out 1-0 winners in May 1983 though manager Chris Hughton will be hoping for the reverse, in what would be one of the biggest opening day shock results in history.

The hosts will be without Anthony Knockheat will be assessed ahead of kick-off as he nears a return from an ankle ligament injury with Beram Kayal and Sam Baldock definitely missing out though Davy Propper, Mat Ryan, Pascal Gross and Markus Suttner could make their debuts.

Glenn Murray is widely available at 13.0 (12/1) to open the scoring with Jamie Murphy is a 23.0 (22/1) chance with Bet 365.

Last season’s Championship runners-up are as highly priced as the 11.0 (10/1) on offer from a variety of firms to take all three points with the visitors firm favourites at 1.34 (1/29) with Unibet. The draw can be backed at 46/10 (5.6) with Sporting Bet.

Pep Guardiola began last season, his first in England with six straight league victories but ended the campaign in third place behind champions Chelsea and Tottenham Hotspur.

They do however begin this season as favourites to win the division having spent over £200m on players this summer and three of those new arrivals could start here.

Kyle Walker, Danilo and Ederson are all in line for their debuts though the game is likely to come too soon for Bernardo Silva who is lacking match fitness and Benjamin Mendy who has a thigh problem.

Sergio Aguero is favourite to get the first goal of the game at 4.0 (3/1) with a number of firms with Kevin De Bruyne a 9.0 (8/1) chance with Betfred.

The two sides have met once since that league clash thirty-four years ago, with Brighton edging out City on penalties in a League Cup tie in September 2009 and Glenn Murray netted in the initial 2-2 draw. You can back both teams to score this time around at 1.87 (20/23) with Bet Victor.