The late goal scored by Rodrigo at Estadio de Gran Canaria put Valencia in the driving seat ahead of the return leg at Mestalla.
Following the 1-1 draw in the first match, los Che have got to be considered favourites to make it through to the next stage of Copa del Rey.
This has been a very successful season for Valencia, who occupy third place in the La Liga standings, although the team have been going through a rough patch of late.
Namely, los Che suffered back to back league defeats to Eibar and Villarreal, while also coming close to losing to Las Palmas in Copa del Rey.
However, Rodrigo Moreno came to the rescue, scoring late after coming on as a second-half substitute for Andreas Pereira.
Valencia since showed a great deal fo character to defeat Girona at home, coming from a goal behind, meaning they head into the Las Palmas clash in great spirits.
Luciano Vietto was handed his debut after arriving from Atletico Madrid, and he will again be in contention, while Andreas Pereira and Geoffrey Kondogbia should start as they are banned for the weekend’s clash with Deportivo.
Probable starting line-up (4-4-2): Domenech – Montoya, Garay, Vezo, Toni Lato – Pereira, Maksimovic, Kondogbia, Nacho Gil – Vietto, Santi Mina.
Midway through the La Liga campaign and Las Palmas sit at rock bottom with just 11 points from 18 games, some five points adrift of safety.
Former Rayo Vallecano boss Paco Jemez has been hired recently to try and arrest the barren run, but the fans are still waiting for fourth La Liga win this season.
Las Palmas have been pretty disappointing of late, taking just one point from last four league fixtures, but they fared well in the first leg of their Copa del Rey clash with Valencia.
Having since squandered a one-goal lead to lose to Eibar at home in La Liga, Paco Jemez’s men will be low on confidence going into the Valencia game.
There were more bad news for Las Palmas as on loan midfielder Sergi Samper suffered a season-ending injury, but Alberto Aquilani is back in contention.
Probable starting line-up (4-2-3-1): Chichizola – David Simon, Galvez, Bigas, Borja Herrera – Aquilani, Toledo – Tana, Viera, Momo – Calleri.