After losing to the same rival in Leverkusen, Valencia need to beat Bayer Leverkusen at Mestalla or they will probably lose all chances to make it to the next round.

Valencia have been pretty inconsistent this season, playing great football in some games, but largely underperforming in others, so it is no wonder they are now in a very difficult position.

Los Che failed to beat Genk away from home, while they were lucky to avoid defeat to Chelsea at Mestalla, so the games against Bayer Leverkusen were always going to be crucial for them.

Unai Emery’s side did well to take the lead at Bay Arena and had several glorious chances to secure the win, but they instead allowed the hosts to get back into the game and ended up losing all three points.

Los Che are now four points behind their next opponents, meaning that this is a must-win game for them, but odds of 1.70 (7/10) offered by William Hill on home win do not represent a real value for money.

Valencia have finally recorded back to back victories in La Liga, having beaten Zaragoza and Getafe, and they are now hoping to make it three in a row.

Excellent keeper Diego Alves is again set to be given a chance to impress, while Sofiane Feghouli could keep his place in the side after scoring a brace against Getafe.

Probable starting line-up (4-2-3-1): Diego Alves – Miguel, Rami, Ruiz, Alba – Albelda, Banega – Hernandez, Feghouli, Mathieu – Soldado.

Bayer Leverkusen are also playing below the expectations, but at least their Champions League showings have been pretty good so far.

After losing to Chelsea in their opening game, die Werkself recorded back to back wins over Genk and Valencia, and are now very close to securing their place in the knockout stages.

However, Robin Dutt’s side are hardly firing on all cylinders at the moment and that could prove to be a problem.

Following the home defeat to Schalke, Bayer Leverkusen produced an under-par performance in the weekend’s game at Freiburg, but somehow managed to record a win, although they will have to show some improvement in order to get something from Mestalla.

Coach Dutt was happy to see Michael Ballack complete a full training session despite breaking his nose at the weekend, with the former Germany international likely to play against Valencia with a protective mask.

Probable starting line-up (4-2-3-1): Leno – Schwaab, Toprak, Friedrich, Kadlec – Ballack, Bender – Castro, Schurrle, Sam – Kiessling.