The Serie A top 3 rivals are set to square off at Stadio San Paolo, and with both Napoli and Roma hoping to stay close to leaders Juventus, we should witness an entertaining clash.

Napoli have enjoyed a pretty good start to the season, taking 14 points from first 6 fixtures, while also winning their first two Champions League fixture.

Summer recruit Arkadiusz Milik was especially impressive, bagging 7 goals in first 9 appearances for the new club, but a lot has changed over the last ten days.

Napoli first damaged their Serie A title chances by losing to Atalanta, before the talented forward picked up a serious knee injury on international duty.

This means that Manolo Gabbiadini will have to step up the plate after impressing in pre-season, and the clash against AS Roma is quite important with regards to how the Azzurri will respond to latest setbacks.

But, having won each of their last ten fixtures at Stadio San Paolo, Napoli look a good bet at 2.00 (1/1) to see off the Giallorossi as well.

You should also bear in mind that Napoli won three of their last four home fixtures against Roma, with the Giallorossi failing to score a single goal in the process.

Arkadiusz Milik is set for a four-month spell on the sidelines, but Raul Albiol and Vlad Chiriches should be back in contention.

Probable starting line-up (4-3-3): Reina – Hysaj, Koulibaly, Albiol, Ghoulam – Allan, Jorginho, Hamsik – Callejon, Gabbiadini, Mertens.

Despite all the effort the club officials have made in recent years, AS Roma cannot seem to catch a break and they have yet to mount a serious title challenge.

The Giallorossi have done pretty well in most games this season, but inconsistency remains the problem, just like on so many occasions in the past.

While that has rarely been the case in the past, AS Roma’s results this season have been quite easy to predict, as they are showing two completely different faces home and away.

The Giallorossi have won each of their four home fixtures in Serie A, but they have only won one point on the road, losing to Fiorentina and Torino, while sharing spoils with Cagliari.

Considering that AS Roma failed to score on their previous four trips to Stadio San Paolo, it is clear that they could face a tough task on Saturday afternoon.

Radja Nainggolan should return to the side after recovering from a muscle problem, but Mario Rui, Antonio Rudiger and Thomas Vermaelen remain sidelined.

Probable starting line-up (4-3-3): Szczesny – Florenzi, Manolas, Fazio, Bruno Peres – Strootman, De Rossi, Nainggolan – Salah, Dzeko, Perotti.