New Wales boss Gary Speed and his players will have a special motive in this match as England are one of their fierce rivals not only in football but in other spheres as well.

Experienced coach John Toshack resigned from the post after losing the first qualifying game to Montenegro, while caretaker boss Brian Flynn couldn’t prevent defeats to Bulgaria and Switzerland.

As a result, Wales are already out of contention for the top two places, meaning new coach Gary Speed will be looking to rebuild the squad during this qualifying campaign and prepare his side for the next one.

The hosts’ preparations for this crucial encounter were dealt with a major blow as Gareth Bale has reportedly picked up an injury in training and he is a major doubt for this clash.

Aaron Ramsey returns to the side after the lengthy injury lay-off, but Robbie Earnshaw has withdrawn through injury.

Wales squad:

Goalkeepers: Wayne Hennessey (Wolverhampton Wanderers FC), Boaz Myhill (West Bromwich Albion FC), Lewis Price (Crystal Palace FC).

Defenders: Danny Collins (Stoke City FC), James Collins (Aston Villa FC), Neil Eardley (Blackpool FC), Danny Gabbidon (West Ham United FC), Chris Gunter (Nottingham Forest FC), Lewin Nyatanga (Bristol City FC), Neil Taylor (Swansea City FC), Ashley Williams (Swansea City FC).

Midfielders: Joe Allen (Swansea City FC), Gareth Bale (Tottenham Hotspur FC), Andrew Crofts (Norwich City FC), Andy King (Leicester City FC), Joe Ledley (Celtic FC), Aaron Ramsey (Arsenal FC), David Vaughan (Blackpool FC).

Forwards: Craig Bellamy (Cardiff City FC), Simon Church (Reading FC), Chedwyn Evans (Sheffield United FC), Freddy Eastwood (Coventry City FC), Steve Morison (Millwall FC), Hal Robson-Kanu (Reading FC), Sam Vokes (Wolverhampton Wanderers FC).

England enter this game amidst controversy over the captain’s armband, which was handed back to John Terry to the disgust of Rio Ferdinand and his fellow teammates.

After failing to beat Montenegro at home, the Three Lions have got to win this game if they want to catch Montenegro at the top, but they will not have an easy job at Millennium Stadium in Cardiff.

Steven Gerrard, Rio Ferdinand and Theo Walcott miss out, while Wolves’ Matt Jarvis will have a chance to earn his first cap.

Andy Carroll and Wayne Rooney are expected to start up front, while Jack Wilshire will keep his place in the side.

England squad:

Goalkeepers: Ben Foster (Birmingham City FC), Robert Green (West Ham United FC), Joe Hart (Manchester City FC).

Defenders: Leighton Baines (Everton FC), Gary Cahill (Bolton Wanderers FC), Ashley Cole (Chelsea FC), Michael Dawson (Tottenham Hotspur FC), Phil Jagielka (Everton FC), Glen Johnson (Liverpool FC), Joleon Lescott (Manchester City FC), John Terry (Chelsea FC), Kyle Walker (Aston Villa FC).

Midfielders: Gareth Barry (Manchester City FC), Stewart Downing (Aston Villa FC), Matt Jarvis (Wolverhampton Wanderers FC), Frank Lampard (Chelsea FC), Aaron Lennon (Tottenham Hotspur FC), James Milner (Manchester City FC), Scott Parker (West Ham United FC), Jack Wilshere (Arsenal FC), Ashley Young (Aston Villa FC).

Strikers: Darren Bent (Aston Villa FC), Andy Carroll (Liverpool FC), Peter Crouch (Tottenham Hotspur FC), Jermain Defoe (Tottenham Hotspur FC), Wayne Rooney (Manchester United FC).

Even though they will not have an easy job in Wales, England are priced 1.44 (4/9) at Bodog, while Wales are 8.00 (7/1) to cause a major upset and win the game.

Watch Wales vs England live stream here. Check this page for the full Live Stream schedule of the Euro 2012 qualifiers.