Manchester City are in a difficult position after the 3-2 defeat at Santiago Bernabeu, so this will feel as a must-win game for the Citizens.
Borussia Dortmund go into the game high on confidence following a 5-0 victory over Borussia M’gladbach at the weekend, and they now aim to make a giant step towards the knockout stages by taking at least one point from Etihad.
Following the strong start to the season, Manchester City have suffered a big dip in form of late, which is certainly a cause for concern.
Roberto Mancini’s side have just ended the four-match winless run as they came from a goal behind to beat Fulham, with the win at Craven Cottage likely to act as much needed confidence boost before the all-important clash against Borussia.
The Citizens were so close to getting something from their opening game against Real Madrid, having taken a one-goal lead into the final stage of the match, but they conceded two late goals and ended up leaving Bernabeu empty handed.
Roberto Mancini has no fresh injury worries ahead of this match, but he is likely to make a couple of changes to the team that beat Fulham at the weekend.
Probable starting line-up (4-2-3-1): Hart – Zabaleta, Kompany, Lescott, Kolarov – Garcia, Barry – Tevez, Y. Toure, Silva – Aguero.
Borussia Dortmund could not get past the group stage last term, and they have once again been handed a very difficult Champions League group.
The Germans did well to record a 1-0 victory over Ajax in their opening game, but things get tough now as they prepare to face Manchester City and Borussia Dortmund.
The good thing is the Millionaires responded well to the league setbacks against Hamburger and Eintracht, having hammered Borussia M’gladbach 5-0 at the weekend, but they are now set to face much more serious opponents.
If Jurgen Klopp’s side get something from Etihad they will make a big step towards the next round, so bear in mind BVB are 2.20 (6/5) with Sportingbet to qualify.
The visitors arrive to England with a fully fit squad, and Robert Lewandowski is set to return to the starting line-up after he was rested at the weekend.
Probable starting line-up (4-2-3-1): Widenfeller – Piszczek, Subotic, Hummels, Schmelzer – Kehl, Gundogan – Blaszczykowski, Gotze, Reus – Lewandowski.