The 2013 finalists Borussia Dortmund face an uphill task in an attempt to reach the Champions League semi-finals for the second year running following the 3-0 defeat in the first leg.

Real Madrid are clearly well in the driving seat, but they will certainly be looking to extend the impressive run at Signal-Iduna Park.

Considering everything thrown their way this term, Borussia Dortmund did really well to get the most out of the current season.

With their key players picking up serious injuries one after another, the Millionaires were unable to mount a serious title challenge in Bundesliga, but following some tough times they have all but secured the second place in the standings.

Meanwhile, Jurgen Klopp’s charges are set to battle Wolfsburg for a place in the DFB Pokal final, although their Champions League campaign seems to be drawing to a close.

With a number of key men missing, Borussia could do little to avoid a 3-0 loss to Real Madrid in the first leg, and they are now 3.50 (5/2) to at least win the return match.

The hosts will have Robert Lewandowski back from suspension, but now captain Sebastian Kehl is banned and keeper Roman Weidenfeller is doubtful.

The likes of Neven Subotic, Sven Bender, Ilkay Gundogan, Marcel Schmelzer and Jakub Blaszczykowski remain on the sidelines.

Probable starting line-up (4-2-3-1): Weidenfeller – Piszczek, Papastathopoulos, Hummels, Durm – Jojic, Sahin – Grosskreutz, Mkhitaryan, Reus – Lewandowski.

After playing some great football throughout the season, Real Madrid suffered back to back defeats to Barcelona and Sevilla that seriously damaged their chances of winning the league title.

And while many believed los Blancos would struggle to return to the right track, they instead impressed in the following three fixtures, defeating Rayo Vallecano, Borussia Dortmund and Real Sociedad.

Having scored a total of 12 goals during that period and kept three successive clean sheets, it is hardly surprising they have been made 2.20 (6/5) favourites to win at Signal-Iduna Park.

Real Madrid produced a very good performance to record a comfortable victory at Anoeta on Saturday and they clearly go into the Dortmund clash high on confidence.

Portuguese superstar Cristiano Ronaldo is set to return into action and he is 1.91 (10/11) with SkyBet to score anytime.

Angel Di Maria has recovered from gastroenteritis and he is available as well, but Alvaro Arbeloa, Marcelo, Sami Khedira and Jese Rodriguez are out injured.

Probable starting line-up (4-3-3): Casillas – Carvajal, Pepe, Ramos, Coentrao – Modric, Alonso, Di Maria – Bale, Benzema, Ronaldo.