Bottom-placed Espanyol hope to boost their survival chances with three points from this match, while Sevilla aim to make amends for back to back defeats to Atletico Madrid and Real Valladolid.
After they did so well over the last couple of years, everyone was surprised to see los Periquitos struggle at the start of the new league campaign.
Boss Mauricio Pochettino was sacked following the disappointing run of results, with Javier Aguirre taking charge of the team.
The Mexican coach didn’t have the best of starts as his side were beaten at home by Sevilla in Copa del Rey, although los Periquitos ended their losing run by bringing one point from Granada last weekend.
Espanyol will now aim to get revenge on Sevilla for the aforementioned defeat, with the hosts 2.80 (9/5) with William Hill to finally return to winning ways.
Striker Carlos Stuani could be available despite the fractured cheekbone, and another good news is that boss Javier Aguirre has no fresh injury worries.
Probable starting line-up (4-2-3-1): C. Alvarez – Javi Lopez, Forlin, Colotto, V. Alvarez – V. Sanchez, Baena – Simao, Verdu, Mubarak – Longo.
Sevilla have been on a major downtrend following what was a bright start to the season, and los Rojiblancos continue to slip down the La Liga standings.
Rather than serving as a huge confidence boost, the 5-1 derby win over Real Betis seems to have had a negative effect on the team, as they went on to record two very disappointing results in La Liga.
While beating ten-man Espanyol in Copa del Rey, Sevilla suffered back to back league defeats to Atletico Madrid and Rayo Vallecano, and now have no choice but to try and win in Barcelona.
With several important players back to the side, los Rojiblancos are 2.63 (13/8) with Stan James to triumph at Cornella El Prat.
Emir Spahic, Ivan Rakitic and Federico Fazio all return from suspension, but now Antonio Luna and Gary Medel are banned.
Manu del Moral is back in contention after recovering from injury, whereas Alvaro Negredo and Hedwiges Maduro are doubtful.
Probable starting line-up (4-2-3-1): Palop – Cicinho, Spahic, Fazio, Navarro – Kondogbia, Maduro – Navas, Rakitic, Reyes – Manu.