Marseille gained the upper hand of the tie by holding the Turkish side to 1-1 draw in the first leg, but Eskisehirspor will give their best to make life difficult for their opponents in the return leg.
The French giants are coming on the back of one of the most disappointing seasons in their recent history, given that the team that had been tipped to fight for the title finished the league campaign in 10th place, 34 points behind champions Montpellier.
OM qualified for Europa League by winning the Coupe de la Ligue, but they were far from impressive in the first leg against Eskisehirspor, although they did miss several important players.
The squad have suffered virtually no changes apart from the fact that Elie Baup replaced Didier Deschamps, but the big problem is that a number of high-profile players is expected to leave this summer.
With several starters back in the side for the return leg, Marseille look like they can secure the passage into the play-off stage, and they are 1.45 (9/20) with Betfair to win the game in regular time. The price on home win is even lower at other online bookmakers.
Loic Remy, Souleyman Diawara and Leyti N’Diaye remain sidelined, but Alou Diarra and Cesar Azpilicueta are back in contention.
Probable starting line-up (4-3-3): Mandanda – Azpilicueta, M’Bia, N’Kulou, Morel – Valbuena, Diarra, Cheyrou – Amalfitano, Gignac, A. Ayew.
Following the 12-year absence from Turkey’s top flight, Eskisehirspor gained promotion to the Super Lig in 2008 and they have been on the constant uptrend ever since.
The team finished last league campaign in 5th place to ensure their first ever European qualification, but were very unfortunate to be drawn alongside Marseille.
The Turks, nonetheless, played well against their more illustrious opponents and earned a 1-1 draw that leaves them some hope before the return leg in France.
Former Borussia Dortmund full-back Dede, former Fulham striker Diomansy Kamara and experienced defender Servet Cetin are expected to help their younger teammates in this high-profile clash that will be played at Stade Parsemain in Fos sur Mer since Velodrome is undergoing reconstruction work.
Sezgin Coskun misses out through injury, whereas striker Batuhan Karadeniz is out of contention after clashing with coach Ersun Yanal.
Probable starting line-up (4-3-2-1): Boffin – Veysel, Servet Cetin, Diego, Dede – Tello, Hurriyet, Alper – Erkan, Malecki – Kamara.